Calcium Oxalate Kidney Stones For Everyone. #2B. What Causes Calcium Oxalate Kidney Stones?

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Increased Oxalate Absorption.

Some people’s intestines absorb more oxalate than others. If more than 15% of the ingested oxalate is absorbed a person is considered a oxalate hyperabsorber. Increased oxalate absorption results in hyperoxalemia, followed by hyperoxaluria, leading to calcium oxalate stone formation.

Oxalate can be absorbed at a greater rate if the enteric content of calcium is decreased. Calcium readily binds to oxalate in the gut, so, if the oral intake of calcium-containing food is decreased more oxalate will be absorbed. Finally, in cases of increased fat in the intestines such as in fat malabsorption or when the diet contains too much fat, calcium ends up binding to fat, decreasing its ability to chelate oxalate.

Knight, John, Juquan Jiang, Ross P. Holmes, Kyle D. Wood, and Dean G. Assimos. “Oxalate and Sucralose Absorption in Idiopathic Calcium Oxalate Stone Formers." Urology 78, no. 2 (2011): 475.e9-475.e13. doi:
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Any information or statement present in this post does not replace your health care provider’s advice or treatment. This blog does not provide medical advice, prescribe medications or therapies, or diagnose conditions, it only expresses an opinion. If you have a health-related question or condition, confer with your healthcare provider.
- In order to quote this article in a bibliography please use the following (Chicago Style):
Ramos, Marco.“Calcium Oxalate Kidney Stones For Everyone. #2B. What Causes Calcium Oxalate Kidney Stones?”. SMO Blog (blog). Second Medical Opinions PLC, February 6, 2020.

Read the other sections of this series:

What Causes Calcium Oxalate Kidney Stones? A

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© 2020 Second Medical Opinions PLC. All rights reserved

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07.02.2020 03:59